CD14 Employs Hydrophilic Regions to “Capture” Lipopolysaccharides
نویسندگان
چکیده
منابع مشابه
CD14 employs hydrophilic regions to "capture" lipopolysaccharides.
CD14 participates in the host innate inflammatory response to bacterial LPS obtained from Escherichia coli and other Gram-negative bacteria. Evidence from several laboratories suggests that different regions of the amino-terminal portion of the molecule may be involved in LPS binding. In this report a series of single-residue serine replacement and charge reversal mutations were generated to fu...
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2000
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.164.6.3255